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Furthermore, Montfort and colleagues showed in MAT1A −/− mice a reduced SOD activity, possibly due to an increase in oxidative stress [96]

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The gut microbiome, shaped by genetic, environmental, and lifestyle factors, plays a crucial role in immune, metabolic, and neural development, with dysbiosis increasingly implicated in the pathogenesis of neurological disorders such as stroke, PD, and AD (Sorboni et al., 2022)